abstract：:The degradation of poly[bis(glycine ethyl ester)phosphazene] in aqueous media was studied by following the appearance of some of its expected by-products in solution. Disc-shaped polymer slabs of 12 mm diameter and 1.2 mm thickness were prepared by compression moulding, followed by incubation in aqueous media under ca...

journal_title：Biomaterials

authors： Ruiz EM,Ramírez CA,Aponte MA,Barbosa-Cánovas GV

更新日期：1993-06-01 00:00:00

abstract：:Four commercial hydroxyapatites (both natural and synthetic) were tested to assess transformations of the chemical and crystalline structure following variation of temperature from 20 to 1600 degrees C. The thermal behaviour of hydroxyapatite is relevant for biomedical applications such as plasma spraying of metallic ...

journal_title：Biomaterials

authors： Locardi B,Pazzaglia UE,Gabbi C,Profilo B

更新日期：1993-05-01 00:00:00

abstract：:Beads of polytetrafluoroethylene were used to investigate adsorption of thrombin and the influence of the adsorbed protease on a subsequent deposition of fibrinogen. Adsorption of active thrombin was not detected by a specific fluorogenic substrate unless > 0.1 units/ml had been applied. Adsorption was considerably im...

journal_title：Biomaterials

authors： Schlosser E,Simler R,Hörmann H

更新日期：1993-04-01 00:00:00

abstract：:The adherence of five strains of Staphylococcus epidermidis and one strain of S. aureus to both untreated and Hydromer-coated silicone rubber cerebrospinal fluid shunts was studied in vitro using epifluorescent image analysis. All five strains of S. epidermidis showed similar levels of adherence to untreated shunts, w...

journal_title：Biomaterials

authors： Bridgett MJ,Davies MC,Denyer SP,Eldridge PR

更新日期：1993-02-01 00:00:00

abstract：:Primary rat bone marrow cells were cultured for periods of 8 d on hydroxyapatite discs produced by sintering compressed powder at 1130 degrees C. The disc surfaces were roughened using silicon carbide paper to create three groups of samples (n = 10) of differing surface topography. The culture conditions permitted bot...

journal_title：Biomaterials

authors： Gomi K,Lowenberg B,Shapiro G,Davies JE

更新日期：1993-01-01 00:00:00

abstract：:Anchorage-dependent cells (NRK 49F) were grown at 37 degrees C in serum containing medium on glass coated with a N-isopropyl acrylamide/N-t-butyl acrylamide copolymer (NIPAaM/NTBAM) with a lower critical solution temperature (LCST) of 8 degrees C. After incubating the dishes and adherent cells at 4 degrees C for 1 h, ...

journal_title：Biomaterials

authors： Rollason G,Davies JE,Sefton MV

更新日期：1993-01-01 00:00:00

abstract：:Right femoral, cortical bone osteotomies of 42 rabbits were fixed with fibrillated, self-reinforced (SR) poly-L-lactide (PLLA) rods, 4.5 mm in diameter. Follow-up times were from 3 to 48 wk. None of the rods broke during this period. There was one non-union at three weeks and one non-union at 12 weeks. Radiographic, h...

journal_title：Biomaterials

authors： Manninen MJ,Pohjonen T

更新日期：1993-01-01 00:00:00

abstract：:Cell detachment by laminar shear stresses was used to characterize cellular interactions with hydrophilic glass and hydrophobic silane. In this study, we examined whether smaller, rounder cells were preferentially detached by laminar flow, and whether cell detachment occurred by dissociation of adhesion proteins and t...

journal_title：Biomaterials

authors： Truskey GA,Proulx TL

更新日期：1993-01-01 00:00:00

abstract：:To study the effect of ionizable functional groups on the adhesion of leucocytes to surfaces, both poly(ethyleneimine) and poly(acrylic acid) were immobilized on polyurethane films, resulting in the introduction of amine and carboxylic acid groups, respectively. This was confirmed by contact angle measurements and XPS...

journal_title：Biomaterials

authors： Bruil A,Terlingen JG,Beugeling T,van Aken WG,Feijen J

更新日期：1992-01-01 00:00:00

abstract：:The aminohexyl derivative of the copolymer of 2-hydroxyethyl methacrylate and ethylene dimethacrylate (p(HEMA)-Hex) in the form of regular spherical particles was used as a polymeric carrier for chemically sorbed methotrexate (MTX). The effect of the washed p(HEMA)-Hex-MTX carrier on the morphological structure of don...

journal_title：Biomaterials

authors： Horák D,Svec F,Adamyan A,Titova M,Skuba N,Voronkova O,Trostenyuk N,Vishnevskii V,Gumargalieva K

更新日期：1992-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an autoimmune disease. Antibodies directed mainly against DNA and/or phospholipids are present in the serum of SLE patients. Therefore phosphorylated polystyrene derivatives acting as DNA-like polymers should be able to interact with the SLE anti-DNA antibodies. Such functional po...

journal_title：Biomaterials

authors： Letourneur D,Jozefowicz M

更新日期：1992-01-01 00:00:00

abstract：:Glucose oxidase was immobilized into photographic gelatin hardened by chromium(III) sulphate. The enzyme-gelatin mixture was coated on polyester film strips which allowed easy and simple handling during assays. The effect of gelatin and cross-linker concentrations on water content and enzymatic activity was studied. T...

journal_title：Biomaterials

authors： Elçin YM,Akbulut U

更新日期：1992-01-01 00:00:00

abstract：:Fibrous polyurethane (FPU) prostheses with or without fibronectin coating and gelatin impregnation and FPU prostheses with or without fibronectin coating were seeded with 4.8 x 10(5) subcultivated dog endothelial cells per cm2 prosthesis. Expanded polytetrafluoroethylene (ePTFE) prostheses with and without fibronectin...

journal_title：Biomaterials

authors： Hess F,Jerusalem R,Reijnders O,Jerusalem C,Steeghs S,Braun B,Grande P

更新日期：1992-01-01 00:00:00

abstract：:Previous studies have shown that high impact strength can be conferred on denture-base poly(methyl methacrylate) polymers by modification with acrylic-terminated butadiene-styrene block copolymers, and that the acrylic end-group was necessary for effective reinforcement. It is now shown that, by solvent extraction stu...

journal_title：Biomaterials

authors： Rodford RA,Braden M

更新日期：1992-01-01 00:00:00

abstract：:Six routinely packaged commercially pure titanium dental implants (three commercial brands) were analysed using secondary ion mass spectrometry to examine the outermost surface layer. The aim of the analysis was to compare the surface purity (99.95%) of the implants with the substrate metal, common to all three brands...

journal_title：Biomaterials

authors： Edwards BN,Gold BR

更新日期：1992-01-01 00:00:00

abstract：:To evaluate the biocompatibility of chemically and structurally modified polyurethane elastomers for use as blood vessel replacements, small squares of vascular prostheses were cultured in direct contact with endothelium from chick embryo aorta using an organotypic culture assay. The polyurethane materials tested were...

journal_title：Biomaterials

authors： Guidoin R,Sigot M,King M,Sigot-Luizard MF

更新日期：1992-01-01 00:00:00

abstract：:A procedure for preparing homogeneous chitosan gels by in situ molybdate cross-linking is described. The gels are obtained by dispersing solid MoO3 in a buffered chitosan solution and the polymer is cross-linked by formation of heavily negatively charged molybdate polyoxyanions. The resulting ionic gels are very trans...

journal_title：Biomaterials

authors： Draget KI,Vårum KM,Moen E,Gynnild H,Smidsrød O

更新日期：1992-01-01 00:00:00

abstract：:A graft copolymer having poly(L-lysine) (PLL) as the backbone and monomethoxy poly(ethylene glycol) (MPEG) as pendent chains was synthesized. This polycationic copolymer was used to form microcapsules with sodium alginate, a polyanion. Microcapsules and model surfaces formed with PLL-graft-MPEG demonstrated reduced pr...

journal_title：Biomaterials

authors： Sawhney AS,Hubbell JA

更新日期：1992-01-01 00:00:00

abstract：:Films of polyoxyethylene network were prepared from two types of triethoxysilane-terminated prepolymers. In this way, films of polyoxyethylene network with possible applications in the biomedical field could be made easier. To test their biocompatibility, these networks were added to organ cultures of adult human skin...

journal_title：Biomaterials

authors： Beele H,Thierens H,Deveux R,Goethals E,de Ridder L

更新日期：1992-01-01 00:00:00

abstract：:The microstructure of TiTa30 alloys diffusion bonded to a 99.7 wt% Al2O3 ceramic was subdivided into a reaction double layer containing the intermetallic phases TiAl and Ti3Al and the (alpha + beta) Ti microstructure. Excellent fracture toughness data of the TiTa30/Al2O3 joints of about 37 J/m2 were obtained after wel...

journal_title：Biomaterials

authors： Gibbesch B,Elssner G,Petzow G

更新日期：1992-01-01 00:00:00

abstract：:Surface sensitive spectroscopies, Auger electron and X-ray photoelectron (XPS), were used to determine changes in titanium oxide composition, oxide stoichiometry, and adsorbed surface species as a function of exposure to human serum in a balanced electrolyte (serum/SIE) and 8.0 mM ethylenediaminetetraacetic acid in a ...

journal_title：Biomaterials

authors： Healy KE,Ducheyne P

更新日期：1992-01-01 00:00:00

abstract：:An independent assessment was performed of the results of woven carbon implants of mesh or rods into articular cartilage defects performed by two surgeons in the knees of 96 patients. Eight had symptomatic osteochondritis, 31 had chondromalacia patellae and 57 had early osteoarthritis. They were reviewed up to 5 yr af...

journal_title：Biomaterials

authors： Pongor P,Betts J,Muckle DS,Bentley G

更新日期：1992-01-01 00:00:00

abstract：:Five Garren-Edwards Gastric Bubbles were characterized, following up to 4 months use in vivo, using size exclusion chromatography, differential scanning calorimetry and attenuated total reflectance infrared spectroscopy. These techniques show that the material used to construct the bubble is probably an aromatic polye...

journal_title：Biomaterials

authors： Dillon JG,Hughes MK

更新日期：1992-01-01 00:00:00

abstract：:Very pure hydroxyapatite is diamagnetic and shows no electron paramagnetic resonance (EPR) spectrum. Plasma-sprayed coatings made with such a pure hydroxyapatite contain paramagnetic point-defects. Irradiated deposits show a strong EPR absorption assigned to an O2- anion adjacent to a calcium vacancy, with anisotropic...

journal_title：Biomaterials

authors： Sharrock P,Bonel G

更新日期：1992-01-01 00:00:00

abstract：:Artificial meniscal lesions extending into the avascular part of the meniscus, which do not heal by any other means, were repaired by suturing either a porous polymer implant or a synovial flap into the defect. The implant guided the ingrowth of vascular repair tissue into the defect. This fibrous tissue later on tran...

journal_title：Biomaterials

authors： Klompmaker J,Jansen HW,Veth RP,de Groot JH,Nijenhuis AJ,Pennings AJ

更新日期：1991-11-01 00:00:00

abstract：:Covalent immobilization of cell-adhesive proteins such as collagen and fibronectin on to the surface of poly(vinyl alcohol) hydrogel was investigated by using diisocyanates, polyisocyanates, and cyanogen bromide. It was found that 0.5 and 12 micrograms/cm2 of collagen were immobilized on to the surface by using hexame...

journal_title：Biomaterials

authors： Kobayashi H,Ikada Y

更新日期：1991-10-01 00:00:00

abstract：:The flexural strength of five glass ionomers was measured at intervals ranging from 1 h to 3 months after mixing. The pattern of change in flexural strength is material-specific with two water-activated materials having significantly higher long-term flexural strengths than the others. This may be attributable to the ...

journal_title：Biomaterials

authors： Pearson GJ,Atkinson AS

更新日期：1991-09-01 00:00:00

abstract：:Three proprietary dental resins were found to include acrylates (as distinct from methacrylates). As acrylates are well known to have adverse skin reactions, the nature and content of the acrylates were obtained. One resin contained methyl acrylate, and the other two ethyl acrylate. Also, the extractable free monomer ...

journal_title：Biomaterials

authors： Davy KW,Braden M

更新日期：1991-08-01 00:00:00

abstract：:The neutrophil polarization assay, a technique used to measure chemotaxis, was adapted to examine complement activation. Complement activation in serum which had been incubated with metallic and polymeric biomaterials was examined using the neutrophil polarization assay and immunoelectrophoresis assay. In agreement wi...

journal_title：Biomaterials

authors： Remes A,Williams DF

更新日期：1991-08-01 00:00:00

abstract：:Dextran T40 was modified with carboxylic, benzylamide and benzylamine-sulphonated groups (samples 1-10). The polymers were incubated with dextranase and the decrease of molecular weight was determined by high performance size exclusion chromatography. It was shown that the higher the substitution of dextrans, the lowe...

journal_title：Biomaterials

authors： Crepon B,Jozefonvicz J,Chytry V,Rihová B,Kopecek J

更新日期：1991-08-01 00:00:00

abstract：:Samples of linear (additionally crosslinked) p(HEMA) with different amounts of fibrillar collagen were implanted into the popliteal region of rats. After 3 month, the implanted materials were harvested and examined by SEM. The implants underwent marked structural or morphological changes. While the fibrillar collagen ...

journal_title：Biomaterials

authors： Stol M,Cífková I,Tyrácková V,Adam M

更新日期：1991-07-01 00:00:00

abstract：:Polyurethane microspheres having diameters in the range 150-1500 microns were prepared by condensation polymerization of toluene diisocyanate (TDI) with poly(tetramethylene glycol) (PTMG) of average mol wt 990 in an aqueous dispersion medium containing dioctyl sulphosuccinate (DOS) as the suspension stabilizer and 1,4...

journal_title：Biomaterials

authors： Thanoo BC,Sunny MC,Jayakrishnan A

更新日期：1991-07-01 00:00:00

abstract：:Coralline hydroxyapatite ceramics alone (control) and the ceramics combined with rat marrow cells were implanted subcutaneously in the backs of syngeneic Fischer rats and harvested at 1,2,3,4,6,8 and 24 wk after surgery. None of the control ceramics (without marrow) showed bone formation. However, ceramics combined wi...

journal_title：Biomaterials

authors： Okumura M,Ohgushi H,Tamai S

更新日期：1991-05-01 00:00:00

abstract：:A collagen prosthesis was developed as a dural substitute. It is composed of a Dallop matrix-polyester knitted net with radiation cross-linked collagen on both sides. Collagen was derived from enzyme-treated bovine Achilles tendons. Improved hydrophilic properties of the polyester base ensuring stronger adhesion to co...

journal_title：Biomaterials

authors： Pietrucha K

更新日期：1991-04-01 00:00:00

abstract：:Heat treatment of an MgO-CaO-SiO2-P2O5 glass gave a glass ceramic containing crystalline apatite (Ca10(PO4)6O,F2] and beta-wollastonite (CaO,SiO2) in an MgO-CaO-SiO2 glassy matrix. It showed bioactivity and a fairly high mechanical strength which decreased only slowly, even under load-bearing conditions in the body. I...

journal_title：Biomaterials

authors： Kokubo T

更新日期：1991-03-01 00:00:00

abstract：:Biological heart prostheses present medium and long-term problems, owing to progressive deterioration and calcification of the tissue. To study the latter problem, we compared the effectiveness of anticalcification treatments in calf pericardium samples implanted into female Wistar rats after the following procedures:...

journal_title：Biomaterials

authors： Jorge-Herrero E,Gutiérrez MP,Castillo-Olivares JL

更新日期：1991-03-01 00:00:00

abstract：:Poly(vinyl alcohol)-heparin hydrogels with varying water content were synthesized for use as sensor catheter membranes. Films were cast from aqueous mixtures of poly(vinyl alcohol) (PVA), a photosensitive cross-linker p-diazonium diphenyl amine polymer (PA), glutaraldehyde (GA) and heparin. After drying, the films wer...

journal_title：Biomaterials

authors： Brinkman E,van der Does L,Bantjes A

更新日期：1991-01-01 00:00:00

abstract：:Although an expanded polytetrafluoroethylene patch is a suitable synthetic material to repair large abdominal wall defects, lack of tissue ingrowth into the patch may give rise to herniation at the fascia-patch interface. This study was undertaken to determine whether perforations and/or ethanol pretreatment improved ...

journal_title：Biomaterials

authors： Simmermacher RK,van der Lei B,Schakenraad JM,Bleichrodt RP

更新日期：1991-01-01 00:00:00

abstract：:Polydimethylsiloxanes exhibit hydrophobic behaviour and poor wettability. These features impose some problems with the clinical performance of the material when used for the construction of intraoral and extraoral facial prostheses. Surface active agents were added to modify the surface energy of the polydimethylsilox...

journal_title：Biomaterials

authors： Polyzois GL,Winter RW,Stafford GD

更新日期：1991-01-01 00:00:00

abstract：:At the present time, three poly(ortho ester) systems have been described. The first one was developed at the Alza Corporation and is prepared by the transesterification reaction between a diol and diethoxytetrahydrofuran. It is currently marketed under the trade name of Alzamer. A second poly(ortho ester) system, deve...

journal_title：Biomaterials

authors： Heller J

更新日期：1990-11-01 00:00:00